How Do Nootropics Work?

In order to understand what nootropics can do for your brain and your productivity, you have to know how they work. This is a bit of a complicated question, as there are several different types of nootropics, and they all affect the brain in different ways. Know how different nootropics work can help you create a regimen of brain boosters.


Ampakines work by affecting glutamic activity in the brain. They are considered some of the most powerful and effective nootropics. Ampakines stimulate the AMPDA and NDMA glutamate receptors. Ampakines improve attention span, alertness, memory recall, and ability to learn. Recently, the Department of Defense began studying ampakines to see if they may be able to improve military performance.

B-Vitamin Derived Nootropics

It has long been known that B vitamins have a positive influence on cognitive function. Those with B vitamin deficiencies may notice sleepiness, depression, inability to concentrate, and slower reaction times. B-vitamin derived nootropics use the most efficient parts of B vitamins to improve various aspects of cognitive function. They do this by affection methylation and homocyesteine levels.

Choline and Acetylcholine Nootropics (Cholinergics)

These nootropics work by affect acetylcholine, a neurotransmitter used by the brain. Acetylcholine is the most important neurotransmitter for memory formation. Cholinergic nootropics work by making acetylcholine more available in the brain, so the brain can more readily use it for memory creation. There are several categories within cholinergics, including acetylcholine precursors, acetylcholine cofactors, and acetylcholinesterase inhibitors. They all work in slightly different ways, so some people may use multiple cholinergics together.

Natural Nootropics

These nootropics work in many different ways, since they are derived from natural sources. They differ from other types of nootropics in that they are not created by pharmaceutical companies. They may be available as over the counter supplements, while more concentrated forms of natural nootropics may still require a prescription.

Natural nootropics also often fall into any one of the categories listed on this page, as they work on the brain in different ways. For example, huperzine A is a nootropic that is derive from firmoss. This is a natural nootropic, but it is also a cholinergic. Huperzine A is a acetylcholinesterase inhibitor, which keeps the body from prematurely breaking down acetylcholine. However, other natural nootropics do not fit into other categories. Vinpocetine is a natural alkaloid that comes from the periwinkle plant. It is a vasodilator, which improves cerebral blood flow. As a result, users experience better overall brain function.

Peptide Nootropics

Peptide nootropics are often used in combination with other cognitive enhancers. While other nootropics improve the amount of neurotransmitters in the brain, peptide nootropics enhance the brain's neurotransmitter receptors. This makes other nootropics even more effective. The effects of these nootropics include better memory, enhanced reflexes, and an improvement in logical thinking.


Racetams are a big class of nootropics, so they work in several different ways. They may modulate acetylcholine systems, affect muscarinic receptors, and modulate AMPA receptors. These are the most widely studied nootropics, so they are considered the safest.

Visit Site